Category
Pemetrexed
CAS Number
Pemetrexed STD-137281-23-3; 357166-29-1(DiNa Heptahydrate salt); 150399-23-8(Disodium salt): IMP-A-869791-42-4: IMP-D-144051-68-3; 1265908-59-5(TriNa Salt): IMP-E-182009-04-7; 937370-10-0(DiNa Salt)
Molecular Formula
Pemetrexed STD-C20H21N5O6: IMP-A-C21H23N5O6: IMP-D-C25H28N6O9: IMP-E-C20H21N5O6
Molecular Weight
Pemetrexed STD-427.41: IMP-A-441.44: IMP-D-556.52: IMP-E-427.42
Synonym

Pemetrexed STD-(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; NSC 698037 (USP)

Pemetrexed-IMP-A-(2S)-2-[4-[2-(2-amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid

Pemetrexed-IMP-D-(2S)-2-[(4S)-4-[4-[2-(2-amino-4-oxo-4,7-dihydro-1Hpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]-4-carboxybutanamido]pentanedioic acid

Pemetrexed-IMP-E- (2R)-2-[4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid

Slide 1.GIF
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Pemetrexed for System Suitability CRS used to verify the performance of the chromatographic system by evaluating parameters like resolution, repeatability, and retention time during system suitability testing before sample analysis.