Category
Nitroso Amines
CAS Number
NA
Molecular Formula
C13H18N6O
Molecular Weight
274.33 g/mol
Synonym

(N-methyl-N-((3R,4R)-4-methyl-1-nitrosopiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine); Tofacitinib N-Nitroso impurity

Keywords
Impurities
Nitrosamine Standards
Metabolites.
Pharmaceutical Standards
Fine Chemicals
Intermediates
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N-Nitroso Tofacitinib is a nitrosamine impurity that can form in the drug Tofacitinib, used to treat rheumatoid arthritis and other autoimmune diseases. It has no therapeutic role and is regarded as potentially carcinogenic, so its presence in medicines is strictly monitored and controlled for patient safety.