Category
Nitroso Amines
CAS Number
3036581-81-1
Molecular Formula
C25H36N2O5
Molecular Weight
444.57 g/mol
Synonym

N-(2-Hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)-N-(6-(4-phenylbutoxy)hexyl)nitrous Amide;  Salmeterol Nitrosamine Impurity; N-Nitroso Salmeterol; (N-(2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)-N-(6-(4-phenylbutoxy)hexyl)nitrous amide);

Keywords
Metabolites.
Impurities
Intermediates
Pharmaceutical Standards
Fine Chemicals
Slide_1

N-Nitroso Salmeterol is a nitrosamine impurity derived from the long-acting β₂-agonist Salmeterol through nitrosation of its secondary amine group. It is mainly used as an analytical reference standard in pharmaceutical quality control to monitor and limit nitrosamine contamination in drug formulations.