Category
Nitroso Amines
CAS Number
3036581-82-2
Molecular Formula
C19H31N3O6
Molecular Weight
397.47 g/mol
Synonym

((2S,3aS,7aS)-1-(N-((S)-1-ethoxy-1-oxopentan-2-yl)-N-nitroso-L-alanyl)octahydro-1H-indole-2-carboxylic acid)

Keywords
Impurities
Impurities
Metabolites.
Pharmaceutical Standards
Nitrosamine Standards
Fine Chemicals
slide.1

N-Nitroso Perindopril is a nitrosamine impurity that can form in the antihypertensive drug Perindopril, an ACE inhibitor used to treat high blood pressure and heart failure. It has no therapeutic application itself; rather, it is considered a potentially harmful contaminant due to its possible carcinogenic (cancer-causing) properties. Regulatory agencies monitor and control the presence of N-nitroso perindopril in pharmaceutical products to ensure drug safety and patient protection.