Category
Nitroso Amines
CAS Number
13010-47-4
Molecular Formula
C9H16ClN3O2
Molecular Weight
233.7 g/mol
Synonym

N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea; 1-(2-Chloroethyl)-1-nitroso-3-cyclohexylurea; Belustine; CCNU; Cecenu; CeeNU; Chloroethylcyclohexylnitrosourea; CiNu; NSC 79037; Urea, N-(2-chloroethyl)-N`-cyclohexyl-N-nitroso;N-(2-Chloroethyl)-N`-cyclohexyl-N-nitrosourea;Urea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso;1-(2-Chloroethyl)-1-nitroso-3-cyclohexylurea;1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea;1-(2-Chloroethyl)-3-cyclohexylnitrosourea;3-Cyclohexyl-1-(2-chloroethyl)-1-nitrosourea;Belustine;Chloroethylcyclohexylnitrosourea;Lomtin;Lomustin;Lustine;Moostine;Lomustine

Keywords
Intermediates
Pharmaceutical Standards
Fine Chemicals
Nitrosamine Standards
Nitric oxide reagents
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1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU, Lomustine) is a nitrosourea anticancer drug used in chemotherapy, primarily for brain tumors, Hodgkin’s lymphoma, and other cancers. It works by alkylating DNA, leading to cancer cell death. Unlike nitrosamine impurities, this compound is therapeutically active.