Category
Nicotine
CAS Number
Nicotine STD-54-11-5: IMP-A-581-49-7: IMP-B-487-19-4: IMP-C-486-56-6: IMP-D-532-12-7; 3079028-57-9 (fumarate salt): IMP-E-491-26-9; 3028194-75-1(oxalate Salt): IMP-F-494-97-3: IMP-G-494-52-0
Molecular Formula
Nicotine STD-C10H14N2: IMP-A-C10H12N2: IMP-B-C10H10N2: IMP-C-C10H12N2O: IMP-D-C9H10N2: IMP-E-C10H14N2O: IMP-F-C9H12N2: IMP-G-C10H14N2
Molecular Weight
Nicotine STD-162.2: IMP-A-160.2: IMP-B-158.2: IMP-C-176.22: IMP-D-146.2: IMP-E-178.24: IMP-F-148.21: IMP-G-162.24
Synonym

Nicotine STD-3-[(2S)-1-methylpyrrolidin-2-yl]pyridine; 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine (as per EP) ; β-Pyridyl-α-N-methyl pyrrolidine (as per USP); (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine

Nicotine-EP-Impurity-A-3-[(2S)-1,2,3,6-tetrahydropyridin-2-yl]pyridine

Nicotine-EP-Impurity-B-3-(1-methylpyrrol-2-yl)pyridine

Nicotine-EP-Impurity-C-(5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one

Nicotine-EP-Impurity-D-3-(3,4-dihydro-2H-pyrrol-5-yl)pyridine

Nicotine-EP-Impurity-E-3-[(2S)-1-methyl-1-oxidopyrrolidin-1-ium-2-yl]pyridine

Nicotine-EP-Impurity-F-3-[(2S)-pyrrolidin-2-yl]pyridine

Nicotine-EP-Impurity-G-3-[(2S)-piperidin-2-yl]pyridine

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Nicotine CRS for System Suitability is used in chromatographic analysis to confirm that the analytical system is functioning properly before testing samples. By injecting the nicotine reference standard, key parameters such as retention time, peak shape, resolution, and theoretical plates are evaluated, ensuring accuracy, precision, and reliability of the chromatographic method for consistent and valid results.