Category
Irinotecan
CAS Number
Irinotecan - 97682-44-5 : IMP - C - 947687-02-7 : IMP - E - 86639-52-3 :
Alternate CAS Number
Irinotecan Hydrochloride Trihydrate -136572-09-3 , HCL - 100286-90-6 ;
Molecular Formula
Irinotecan STD - C33H38N4O6 : IMP - C -C35H42N4O6 : IMP - E - C22H20N2O5
Molecular Weight
Irinotecan STD - 586.68 g/mol : IMP - C - 614.73 g/mol : IMP - E - 392.4 g/mol
Synonym

Irinotecan - (S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4'bipiperidine]-1'-carboxylate ;

Irinotecan EP Impurity - C  - (S)-4,8,11-triethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate ; (S)-4,8,11-Triethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione-9-yl (1,4'-bipiperidine)-1'-carboxylate; (4S)-4,8,11-triethyl-4-hydroxy-3,14-dioxo-3,4,12,14tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin9-yl 1,4'-bipiperidine-1'-carboxylate; 

Irinotecan EP Impurity - E - (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione ; (11-ethyl-9-hydroxycamptothecin) ; (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3`,4`:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;Irinotecan USP Related Compound B ; 

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Irinotecan CRS is used in chromatography to verify accurate peak identification and retention time, ensuring proper system suitability. It helps confirm peak resolution and overall chromatographic performance for reliable quality control.