Methanol

Methanol is a widely used polar solvent in pharmaceutical manufacturing, chemical synthesis, and analytical laboratories. It has the molecular formula CH₃OH, a molecular weight of 32.04 g/mol, and is identified by CAS No. 67-56-1. Due to its toxicity, methanol is tightly regulated and monitored as a residual solvent in active pharmaceutical ingredients (APIs), excipients, and finished drug products.

Accurate determination of methanol is routinely performed using gas chromatography (GC-FID or GC-MS). Reliable analysis requires high-quality GC reference materials and GC analytical reference materials to ensure traceability, accuracy, and reproducibility. GC primary standards serve as the highest-level reference materials for calibration and method validation, while GC secondary standards are used for routine analysis and quality control. In regulated environments, GC compendial standards support compliance with pharmacopeial and regulatory requirements, including USP, Ph. Eur., and JP guidelines. The use of well-characterized methanol GC standards ensures strong method performance, system suitability, and regulatory acceptance.

At Manasa Life Sciences, we provide high-purity methanol GC reference materials, GC analytical reference materials, GC primary standards, GC secondary standards, and GC compendial standards, supported by technical expertise in method development, validation, and regulatory alignment. Our solutions enable accurate methanol quantification and confidence in analytical data integrity across pharmaceutical and industrial applications.