Ethyleneglycol

Ethylene Glycol is a diol widely used in pharmaceutical manufacturing, chemical synthesis, and industrial applications. It has the molecular formula HOCH2CH2OH, a molecular weight of 62.07 g/mol, and is identified by CAS No. 107-21-1. Due to its toxicity, ethylene glycol is monitored as a process-related or organic impurity in pharmaceutical products, excipients, and consumer goods, requiring accurate and sensitive analytical control.

Quantitative determination of ethylene glycol is commonly performed using gas chromatography (GC-FID or GC-MS) after appropriate sample preparation. Ethylene glycol analysis is often included within solvent GC standards, organic impurity GC standards, and broader GC impurity standards used for routine impurity monitoring. In comprehensive analytical workflows, laboratories may also apply fatty acid GC standards in parallel methods, making harmonized GC calibration and impurity control essential. The use of GC impurity profiling standards supports detailed evaluation of impurity patterns and manufacturing consistency. High-quality GC standards, including calibration and reference materials, ensure accuracy, reproducibility, and regulatory compliance during method development, validation, and routine quality control.

At Manasa Life Sciences, we provide high-purity ethylene glycol analytical standards compatible with fatty acid GC standards, solvent GC standards, organic impurity GC standards, GC impurity standards, and GC impurity profiling standards. Our expertise in method development, validation, and regulatory alignment supports accurate ethylene glycol quantification and strong impurity control across pharmaceutical and industrial applications.