Dichloromethane

Dichloromethane (DCM), also known as Methylene Chloride, is a volatile chlorinated solvent widely used in pharmaceutical, chemical, and industrial applications. It has the molecular formula CH₂Cl₂, a molecular weight of 84.93 g/mol, and is identified by CAS No. 75-09-2. Dichloromethane may be present as a residual solvent or process-related impurity in APIs, excipients, and finished drug products, requiring accurate and sensitive quantification.

Accurate determination of DCM is typically performed using gas chromatography (GC-FID or GC-MS). Laboratories trust on high-quality GC standards, GC calibration standards, and GC reference standards to ensure traceability, reproducibility, and regulatory compliance. Certified GC standards, GC analytical standards, and GC certified reference materials (GC CRM standards) provide validated reference values for method development, system suitability, and quality control. Ready-to-use GC calibration solutions and GC standard solutions simplify instrument calibration, method validation, and routine monitoring.

At Manasa Life Sciences, we provide high-purity dichloromethane GC standards, GC calibration solutions, and certified reference materials, along with technical support in method development, validation, and regulatory compliance. Our solutions help laboratories achieve reliable DCM quantification, strong impurity control, and alignment with global analytical standards.