2-Methoxyethanol

2-Methoxyethanol is a glycol ether solvent used in chemical synthesis and industrial processes and is monitored as a regulated impurity due to its reproductive toxicity. It has the molecular formula CH3OCH2CH2OH, a molecular weight of 76.09 g/mol, and is identified by CAS No. 109-86-4. In pharmaceutical manufacturing, 2-methoxyethanol may be present as a residual solvent or process-related impurity, requiring sensitive and reliable analytical control.

Accurate determination of 2-methoxyethanol is routinely performed using gas chromatography (GC-FID or GC-MS) with Pharmacopoeial GC standards to ensure compliance with global regulatory requirements. Laboratories rely on USP GC standards, EP GC standards, BP GC standards, and JP GC standards for method development, system suitability testing, method validation, and routine quality control in accordance with pharmacopeial monographs and guidelines. The use of compendial-aligned GC standards ensures traceability, reproducibility, and regulatory acceptance across different regulatory jurisdictions.

At Manasa Life Sciences, we provide high-purity 2-methoxyethanol Pharmacopoeial GC standards, including USP GC standards, EP GC standards, BP GC standards, and JP GC standards, supported by technical expertise in method development, validation, and regulatory alignment. Our solutions help laboratories achieve accurate quantification, strong impurity control, and global pharmacopeial compliance.