Category
Fluticasone
CAS Number
Fluticasone Propionate - 80474-14-2 ; IMP-G - 220589-37-7; IMP-J- NA : IMP-K- NA
Molecular Formula
Fluticasone Propionate - C25H31F3O5S ; IMP-G - C43H51F5O8S; IMP-J- C25H31F3O5S: IMP-K- C25H31ClF2O5S
Molecular Weight
Fluticasone Propionate - 500.6 g/mol ; IMP-G - 822.9 g/mol ; IMP-J- 500.57 g/mol : IMP-K- 517.0 g/mol
Synonym

Fluticasone Propionate – S-Fluoromethyl 6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-propionyloxyandrosta-1,4-diene-17β-carbothioate

Fluticasone Propionate  EP IMP G- 6alpha,9-difluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 6alpha,9-difluoro-11beta,17-dihydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carboxylate

Fluticasone Propionate  EP IMP J - 6Alpha,9-Difluoro-17-[(fluoromethoxy)carbonothioyl]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17a-yl propanoate;

Fluticasone Propionate  EP IMP K - 6alpha-chloro-9-fluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl propanoate

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Fluticasone propionate CRS is used as a reference standard for system suitability testing in chromatographic analysis to ensure adequate resolution, precision, and reproducibility. It helps verify the performance and reliability of analytical methods for fluticasone propionate formulations.