Category
Etoposide
CAS Number
Etoposide STD - 33419-42-0 : IMP - B - 100007-56-5 : IMP - C - 100007-53-2 :IMP - D - 23363-35-1 : IMP - E - 6559-91-7 : IMP - N - NA : IMP - O - 260974-95-6
Molecular Formula
Etoposide STD - C29H32O13 : IMP - B - C29H32O13 : IMP - C - C29H32O13 :IMP - D - C27H30O13 : IMP - E - C21H20O8 : IMP - N - C50H50O20 : IMP - O - C33H32Cl4O15
Molecular Weight
Etoposide STD - 588.6 g/mol : IMP - B - 588.56 g/mol : IMP - C - 588.56 g/mol :IMP - D - 562.52 g/mol : IMP - E - 400.39 g/mol : IMP - N - 970.92 g/mol : IMP - O - 810.41 g/mol
Synonym

Etoposide - (5R,5aR,8aR,9S)-9-[[4,6-O-[(1R)-ethane-1,1-diyl]-beta-D-glucopyranosyl]oxy]-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydro[2]benzofuro[5,6-f][1,3]benzodioxol-6(5aH)-one ; Furo[3`,4`:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-beta-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S);

Etoposide EP Impurity B - cis-Etoposide ; (5R,5aS,8aR,9S)-9-[[4,6-O-[(R)-ethylidene]-ß-D-glucopyranosyl]oxy]-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydroisobenzofuro[5,6-f][1,3]benzodioxol-6(5aH)-one;

Etoposide EP Impurity C - (5R,5aR,8aR,9S)-9-[[4,6-O-[(R)-Ethylidene]-a-D-glucopyranosyl]oxy]-5-(4- hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydroisobenzofuro[5,6-f][1, 3]benzodioxol-6(5aH)-one ; α-Etoposide ; 

Etoposide EP Impurity D - Lignan P ; (5R,5aR,8aR,9S)-9-(beta-D-Glucopyranosyloxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydro[2]benzofuro-[5,6-f][1,3]benzodioxol-6(5aH)-one ;

Etoposide EP Impurity E - (5R,5aR,8aR,9S)-9-Hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydro[2]benzofuro[5,6-f][1,3]benzodioxol-6(5aH)-one ;

Etoposide EP Impurity N - (5R,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-(((5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)oxy)-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one ;

Etoposide EP Impurity O - (5R,5aR,8aR,9S)-9-[[2,3-Bis-O-(dichloroacetyl)-4,6-O-[(S)-ethylidene]-b-L- glucopyranosyl]oxy]-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9- tetrahydroisobenzofuro[5,6-f][1,3]benzodioxol-6(5aH)-one ; 

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Etoposide is used as a Chemical Reference Standard (CRS) for system suitability testing to ensure the accuracy, precision, and performance of the analytical system. Its well-defined purity and stability support reliable verification of chromatographic parameters during quality control analysis.