Category
Clopidogrel
CAS Number
1258938-54-3
Molecular Formula
C₁₅H₁₇Cl₂NO₂S
Molecular Weight
346.27 g/mol
Synonym

(R)-Methyl 2-(2-chlorophenyl)-2-((2-(thiophen-2-yl)ethyl) amino)acetate hydrochloride;Clopidogrel Open Ring R-Enantiomer;(Methyl(R)-2-(2-chlorophenyl)-2-((2-(thiophen-2-yl)ethyl)amino)acetate,hydrochloride); methyl (2R)-2-(2-chlorophenyl)-2-(2-thiophen-2-ylethylamino)acetate;hydrochloride

Keywords
Impurities
Metabolites.
Pharmaceutical Standards
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Fine Chemicals
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Clopidogrel Open Ring R‑Enantiomer is a specific stereoisomer of clopidogrel that results from the hydrolysis or opening of the lactone (thiolactone) ring in the molecule. It is considered a related impurity and is monitored in pharmaceutical quality control and stability studies to ensure the purity, efficacy, and safety of clopidogrel formulations. This enantiomer retains the R-configuration at the chiral center, which is important for its pharmacological properties and regulatory compliance.