Category
Chemical Primary Standard
CAS Number
76513-69-4
Molecular Formula
C6H15ClOSi
Molecular Weight
166.72 g/mol
Synonym

2-(chloromethoxy)ethyl-trimethylsilane ; 2-(Trimethylsilanyl)ethoxymethyl Chloride; Chloromethyl 2-(Trimethylsilyl)ethyl Ether; Chloromethyl Trimethylsilylethyl Ether; 

Keywords
Miscellaneous compounds
Ethers
Pharmaceutical Intermediates
Chemical Primary Standard
Chemical Primary Standard manufacturers and Suppliers in Hyderabad India
Slide_1

2-(Trimethylsilyl)ethoxymethyl chloride (SEM-Cl) is commonly used as a protecting reagent in organic synthesis, particularly for protecting hydroxyl and nitrogen functional groups during multi-step chemical reactions. It is widely applied in pharmaceutical and fine chemical synthesis to introduce the SEM protecting group, which can later be selectively removed under mild conditions to regenerate the original functional group.