Category
Baricitinib
CAS Number
1187595-89-6
Molecular Formula
C₁₇H₁₉N₇O₃S
Molecular Weight
401.45 g/mol
Synonym

1-(ethylsulfonyl)-3-[4-[7-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-1H-pyrazol-1-yl]-3-Azetidineacetonitrile;2-(1-(Ethylsulfonyl)-3-(4-(7-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile;N-7-Hydroxymethyl Baricitinib ; 1-(ethylsulfonyl)-3-[4-[7-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-1H-pyrazol-1-yl]-3-Azetidineacetonitrile; Ruxolitinib Hydroxy Impurity

Keywords
Metabolites.
Fine Chemicals
Pharmaceutical Standards
Intermediates
Impurities
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

N-7-Hydroxymethyl Baricitinib is a derivative (impurity or metabolite) of Baricitinib formed by the addition of a hydroxymethyl (–CH₂OH) group at the N-7 position of the molecule. It can arise during synthesis or metabolic processes and is monitored in pharmaceutical analysis to ensure it remains within acceptable limits for drug safety and quality.