Category
Apixaban
CAS Number
1777782-31-6
Molecular Formula
C₁₉H₂₄ClN₃O₃
Molecular Weight
377.9 g/mol
Synonym

4-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)butanamide;Butanamide, 4-chloro-N-[4-[5,6-dihydro-3-(4-morpholinyl)-2-oxo-1(2H)-pyridinyl]phenyl]

Keywords
Impurities
Metabolites.
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Apixaban Impurity 48 is a process-related impurity formed during the synthesis of Apixaban. It typically arises from side reactions or incomplete transformations of key intermediates, leading to a structurally related compound that differs slightly from the desired product. This impurity is monitored and controlled using analytical techniques like HPLC or LC-MS, as even trace levels can affect the purity, safety, and quality of the final Apixaban drug substance. It may also be used as a reference standard in impurity profiling and method validation.