Category
Anastrozole
CAS Number
120511-73-1
Alternate CAS Number
868771-60-2(HCl Salt)
Molecular Formula
C₁₇H₁₉N₅
Molecular Weight
293.37 g/mol
Synonym

Anastrozole - API (IP); α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile; 2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile; Anastrazole; Anastrol; Arimidex; 1,3-Benzenediacetonitrile, α,α,α′,α′-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-; α,α,α′,α′-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile (USP)

Keywords
Intermediates
Pharmaceutical Standards
Enzyme inhibitors
Fine Chemicals
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Anastrozole is typically prescribed at a standard oral dose of 1 mg once daily for postmenopausal women with hormone receptor–positive breast cancer. It works by inhibiting the aromatase enzyme, reducing estrogen levels, and thereby slowing the growth of estrogen-dependent tumors. This standard regimen is widely used in both early-stage and advanced breast cancer, either as adjuvant therapy following surgery or as treatment for metastatic disease, due to its effectiveness and generally well-tolerated profile.