Category
Abacavir
CAS Number
136470-78-5
Alternate CAS Number
188062-50-2(Sulphate Salt); 136777-48-5(HCl Salt)
Molecular Formula
C14H18N6O
Molecular Weight
286.33 g/mol
Synonym

[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1S-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ABC; ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol; Abacavir (USP)

Keywords
Intermediates
Pharmaceutical Standards
Enzyme inhibitors
Fine Chemicals
bases and related reagents
Nucleotides
slide.1
Purity:

Above - 95.0%

Technical Data:

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Abacavir is an antiretroviral medication used to treat HIV infection. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs), which work by blocking the reverse transcriptase enzyme, preventing the virus from multiplying. Abacavir is usually taken orally, often in combination with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART). A key safety concern is hypersensitivity reactions, which can be severe; patients are usually tested for the HLA-B*5701 gene before starting treatment to reduce this risk. It helps lower viral load, maintain immune function, and reduce the risk of HIV-related complications.