Impurities

Impurities are undesirable chemical components that remain in the active pharmaceutical ingredient during formulation. Impurities may reduce a product's efficacy.

Amlodipine Maleate Adduct

Amlodipine Maleate Adduct

CAS Number

400602-35-9

70677-78-0

Dimethyl 2,6-Dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS Number

70677-78-0

Valaciclovir Hydrochloride Dihydrate

Valaciclovir Hydrochloride Dihydrate standard

CAS Number

502421-45-6

Amlodipine N-Galactopyranoside

Amlodipine N-Galactopyranoside

CAS Number

NA

C30H34ClN3O8

Hydroxyethyl Phthalyl Amlodipine

CAS Number

NA

Amlodipine Besilate Impurity - D (Fumarate Salt)

Amlodipine Besilate Impurity - D (Fumarate Salt)

CAS Number

2138811-33-1

34148-67-9

Diethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS Number

34148-67-9

2733700-89-3

Amlodipine Besilate Impurity - D (Besilate Salt)

CAS Number

2733700-89-3

C28H28N2O7

3-Ethyl 5-methyl (S)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS Number

NA

Amlodipine Methyl Ester

Amlodipine Methyl Ester

CAS Number

NA

881386-12-5

Apixaban USP Related Compound G

CAS Number

881386-12-5

1267610-26-3

1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one

CAS Number

1267610-26-3

1619934-76-7

Ethyl 1-(4-methoxyphenyl)-7a-morpholino-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-3a,4,5,6,7,7a-hexahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

CAS Number

1619934-76-7

1609409-53-1

Apixaban Impurity E

CAS Number

1609409-53-1

1928718-22-2

1-(4-Ethoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

CAS Number

1928718-22-2

2219376-48-2

3-Chloro-1-(2-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

CAS Number

2219376-48-2

536759-91-8

Apixaban Related Compound F

CAS Number

536759-91-8

1449510-64-8

6-(4-(5- chloropentanamido) phenyl) -1-(4-methoxyphenyl)-7-oxo- 4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c] pyridine-3-carboxamide

CAS Number

1449510-64-8

503615-07-4

Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

CAS Number

503615-07-4

38560-30-4

1-(4-Nitrophenyl)piperidin-2-one

CAS Number

38560-30-4

503614-92-4

Apixaban Carboxylic Acid Impurity

CAS Number

503614-92-4(base)

Alternate CAS Number

1926236-73-8(sodium Salt)

1704504-93-7

6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

CAS Number

1704504-93-7

1466571-07-2

Methyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

CAS Number

1466571-07-2

1074365-84-6

Apixaban Methyl Ester Impurity

CAS Number

1074365-84-6

2203740-09-2

Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate

CAS Number

2203740-09-2

27143-07-3

Ethyl 2-chloro-2-(2- (4-methoxyphenyl) hydrazono)acetate

CAS Number

27143-07-3

2413365-22-5

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)pyridin-2(1H)-one

CAS Number

2413365-22-5

503614-91-3

Apixaban Ethyl Ester Impurity

CAS Number

503614-91-3

2187409-01-2

6-(4-((5-Amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

CAS Number

2187409-01-2

144-62-7

Oxalic Acid

CAS Number

144-62-7

Alternate CAS Number

856335-90-5 (hydrate)

2098457-92-0

1-(4-Methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

CAS Number

2098457-92-0

536760-29-9

3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

CAS Number

536760-29-9

1423803-24-0

6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

CAS Number

1423803-24-0

1643330-62-4

5-Chloro-N-(4-(3-morpholino-2-oxo-5,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide

CAS Number

1643330-62-4

1421823-20-2

Apixaban Related Compound H

CAS Number

1421823-20-2

1351611-14-7

Apixaban Related Compound D

CAS Number

1351611-14-7

503615-03-0

3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

CAS Number

503615-03-0

2077897-93-7

(S)-2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione

CAS Number

2077897-93-7

2055542-18-0

1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-ol

CAS Number

2055542-18-0

1802246-60-1

Apremilast Dimer

CAS Number

1802246-60-1

1384439-79-5

O4-Desmethyl O3-Desethyl Apremilast

CAS Number

1384439-79-5

1450657-31-4

Apremilast Olifin Amine

CAS Number

1450657-31-4

15371-06-9

3-Acetamidophthalic Acid

CAS Number

15371-06-9

1384439-80-8

N-Desacetyl O4-desmethyl O3-desethyl apremilast

CAS Number

1384439-80-8

635705-72-5

Des-acetyl Apremilast

CAS Number

635705-72-5

603-11-2

3-Nitrophthalic Acid

CAS Number

603-11-2

6296-53-3

N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide

CAS Number

6296-53-3

2096492-44-1

Apremilast Hydroxy Impurity

CAS Number

2096492-44-1