Sucralfate is a gastrointestinal medication primarily used for the treatment of ulcers. It is a complex of aluminum hydroxide and sulfated sucrose that works locally in the stomach and duodenum. Unlike many ulcer medications, it does not reduce acid secretion significantly. Instead, it forms a protective barrier over ulcerated or damaged areas in the gastrointestinal lining, preventing further injury from stomach acid and digestive enzymes. Sucralfate is available in tablet or suspension form and is usually taken orally, typically on an empty stomach to maximize its effectiveness.

Uses:

  1. Treatment of active duodenal ulcers.

  2. Management of gastric ulcers.

  3. Prevention of stress-related mucosal damage in critically ill patients.

  4. Treatment of esophagitis, particularly when caused by acid reflux.

  5. Can be used as part of therapy for Gastroesophageal Reflux Disease (GERD) in certain cases.

  6. Helps protect the mucosal lining in patients taking NSAIDs or other ulcerogenic medications.