Simethicone is an over-the-counter anti-foaming agent widely used to relieve symptoms of excessive gas, bloating, and discomfort in the gastrointestinal tract. It works by reducing the surface tension of gas bubbles, causing them to coalesce and be expelled more easily through belching or flatulence. Simethicone is pharmacologically inactive, meaning it is not absorbed into the bloodstream and acts locally in the stomach and intestines. It is commonly included in formulations for infants, children, and adults to manage colic, indigestion, and post-surgical gas. The drug is available in oral drops, chewable tablets, and capsules, offering flexible dosing options. Simethicone is often combined with antacids to provide simultaneous relief from heartburn and gas. Its mechanism of action is purely physical, without altering gastric pH or intestinal function. It is generally considered safe, with minimal side effects even at higher doses. Simethicone is widely used in clinical and household settings for its rapid relief of gas-related discomfort. Overall, it is a simple, effective, and well-tolerated option for managing bloating and flatulence.
