Oxacillin is a semi-synthetic penicillin antibiotic developed to combat penicillin-resistant Staphylococcus aureus infections. It works by inhibiting bacterial cell wall synthesis, making it effective against many Gram-positive bacteria. Oxacillin was first introduced in the early 1960s as part of efforts to create penicillin derivatives resistant to penicillinase enzymes, which break down natural penicillin, providing a more reliable treatment for resistant bacterial infections.
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