Nitrofural, also known as furacilin, is a synthetic nitrofuran derivative introduced in the mid-20th century as an antibacterial agent effective against both Gram-positive and Gram-negative organisms. It was developed during efforts to create stable topical antimicrobials and soon became widely used for wound cleansing, burns, and skin infections due to its broad activity and low resistance rates. Over the decades, nitrofural gained prominence in Eastern Europe and parts of Asia as a reliable antiseptic, particularly in dilute aqueous solutions. Its long history reflects its continued value in topical infection control despite the introduction of newer antimicrobial agents.
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