Nimodipine is a dihydropyridine calcium channel blocker developed in the 1970s and introduced clinically in the 1980s, specifically designed to target cerebral blood vessels. It was developed to prevent and treat neurological complications, particularly cerebral vasospasm following subarachnoid hemorrhage, by selectively dilating cerebral arteries and improving blood flow to the brain. Over time, nimodipine became a standard therapy in neurology for reducing the risk of ischemic brain damage after aneurysmal bleeding.
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