Mometasone is a synthetic corticosteroid widely used for its strong anti-inflammatory, antipruritic, and antiallergic properties. It is commonly prescribed for the management of asthma, allergic rhinitis, and various inflammatory skin disorders. Mometasone works by inhibiting the release of inflammatory mediators and reducing immune responses at the site of application. The drug is available in several formulations, including topical creams and ointments, nasal sprays, and inhalation products. Mometasone furoate is the most commonly used ester form due to its high potency and low systemic bioavailability. It was developed in the late 20th century to improve local efficacy while minimizing systemic side effects. Clinical use expanded as studies demonstrated its safety profile during long-term therapy. Over time, mometasone became a preferred corticosteroid for chronic allergic conditions. Its targeted action makes it suitable for both pediatric and adult patients. Today, mometasone remains an important therapeutic option in respiratory and dermatological care.