Mesterolone is a synthetic androgen and anabolic steroid primarily used to treat male hypogonadism, infertility, and certain conditions associated with low testosterone levels. Structurally related to dihydrotestosterone (DHT), mesterolone exhibits strong androgenic activity with minimal anabolic effects, making it suitable for restoring normal male hormone function without significant muscle-building effects. Developed in the 1960s, it was introduced as a therapeutic agent to address testosterone deficiency and associated symptoms such as low libido, fatigue, and reduced fertility. Over the decades, mesterolone has been valued in clinical practice for its safety profile, oral bioavailability, and effectiveness in improving male reproductive health, while also occasionally being studied for its potential role in sports medicine and hormone replacement therapies.
