Mebeverine is an antispasmodic medication primarily used to relieve symptoms of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders by relaxing the smooth muscles of the gut without affecting normal bowel motility. Developed in the 1960s, mebeverine was introduced as a safer alternative to traditional anticholinergic antispasmodics, which often caused unwanted systemic side effects. Its targeted action on intestinal smooth muscle made it increasingly popular in clinical practice, and over the years it has become a commonly prescribed therapy for abdominal cramps, bloating, and discomfort associated with IBS. Today, mebeverine continues to hold an important place in gastrointestinal management due to its efficacy, tolerability, and long-standing use.
