Dexamethasone sodium phosphate is a water-soluble salt of dexamethasone, a potent synthetic corticosteroid widely used for its anti-inflammatory, anti-allergic, and immunosuppressive effects. It is commonly administered by injection or oral routes when rapid action is required. The drug’s history traces back to the late 1950s, when dexamethasone was developed as a more potent and longer-acting alternative to earlier corticosteroids such as cortisone and hydrocortisone. The sodium phosphate form was later introduced to improve solubility and bioavailability, making it suitable for emergency and hospital use. Since then, dexamethasone sodium phosphate has become an essential medicine in the treatment of severe inflammation, allergic reactions, cerebral edema, and other critical conditions.
