Buflomedil hydrochloride is a vasoactive pharmaceutical compound that was developed to improve blood flow in patients with peripheral circulatory disorders. It works by relaxing blood vessel walls and enhancing microcirculation, which helps increase oxygen delivery to tissues affected by reduced blood supply. Historically, buflomedil was used in the management of peripheral arterial occlusive disease, including intermittent claudication. However, due to safety concerns related to its narrow therapeutic range and potential neurological and cardiac side effects, its clinical use has been restricted or discontinued in many countries.
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