Pemetrexed is a chemotherapy medication widely used in the treatment of certain types of cancer, especially non-small cell lung cancer and malignant pleural mesothelioma. It belongs to a class of drugs known as antifolates, which interfere with the formation of DNA and RNA in cancer cells. By blocking key enzymes needed for cell growth, pemetrexed helps slow down or stop the spread of cancer cells. The drug is usually given by intravenous infusion under medical supervision. Pemetrexed is often used alone or in combination with other anticancer drugs such as cisplatin. To reduce side effects, patients are commonly given folic acid and vitamin B12 supplements. Common side effects include fatigue, nausea, and low blood cell counts. Pemetrexed has shown improved survival benefits in specific cancer patients. Its targeted mechanism makes it an important drug in modern chemotherapy. Overall, pemetrexed plays a significant role in cancer treatment and ongoing oncology research.
