Organic nitroso compounds are chemical substances containing the nitroso-functional group (–N=O) bonded to a carbon atom. They are widely used in organic synthesis, chemical research, and pharmaceutical studies due to their reactivity and ability to form nitrosamine formation products. These compounds can also appear as nitrosamine impurity targets in certain drugs, classified under nitrosamine impurity designation as nitrosamine high-priority impurities, nitrosamine method-defined impurities, nitrosamine standardized impurities, or nitrosamine quantifiable residues. Their presence may arise during the nitrosamine manufacturing process or as nitrosamine drug substance-related impurities, making careful monitoring essential due to their potential carcinogenic risk.
Manasa Life Science supplies high-quality organic nitroso compounds, supporting pharmaceutical research, analytical testing, and regulatory compliance. We offer a comprehensive range of N-nitrosated compounds, such as NDMA, NDEA, NDPA, and NDBA, all carefully synthesized and validated as nitrosamine standardized impurities. Our expertise also supports the assessment of nitroso-derived impurities and N-nitroso derivatives, enabling precise monitoring, classification, and control of nitrosamine levels to ensure safety and regulatory compliance.