N-nitroso derivatives are compounds where a nitroso group (-N=O) is attached to the nitrogen of an amine or amide, typically formed by nitrosation of secondary amines. Many, especially nitrosamines, are biologically active but highly carcinogenic. In pharmaceuticals, they appear as N-nitrosated substances or nitroso-derived impurities and are considered high-priority, non-threshold, quality-impact, process, and regulatory-risk compounds that require strict control.
Manasa Life Sciences is a trusted manufacturer and supplier of nitrosamine quality impact compounds, non-threshold impurities, and regulatory-risk compounds to pharmaceutical companies, CROs, and research labs worldwide. Their portfolio includes regulated nitrosamines like NDMA, NDEA, NDPA, and NDBA, all supplied with full documentation and verified data. With fast processing, regulatory support, and expert guidance, the company ensures consistent quality, traceability, and compliance across Asia, Europe, Africa, the GCC, and the UAE.
Manasa Life Sciences is a globally recognized manufacturer of nitrosamine-associated impurities, providing scientifically validated reference standards that support pharmaceutical research, method development, and regulatory compliance.