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Category
Levodopa
CAS Number
5796-17-8
Molecular Formula
C9H11NO4
Molecular Weight
197.19
Catelogue Number
MLS-LEV-EP-IMP-D/01
Synonym
(+)-3-(3,4-Dihydroxyphenyl)alanine;|(+)-Dopa;|(+)-Dopa; D-3-Hydroxytyrosine;|(R)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid ;|+)-3-(3,4-Dihydroxyphenyl)alanine;|�-(3,4-Dihydroxy)-D-phenylalanine;|3-Hydroxy-D-tyrosine;|D-3-Hydroxytyrosine;|D-3,4-Dihydroxyphenylalanine;|D-Dopa|Levodopa EP Impurity D|Levodopa EP Impurity D ; D-Dopa ; (2R)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid ;|Levodopa EP Impurity D (3,4-Dihydroxy-D-Phenylalanine)|β-(3,4-Dihydroxy)-D-phenylalanine;
Keywords
Amino Acids & Derivatives
Aromatics
Neurochemicals
Pharmaceuticals
Intermediates & Fine Chemicals
Levodopa EP Impurity D
Applications: 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.