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Category
Levodopa
CAS Number
27244-64-0
Molecular Formula
C9H11NO5
Molecular Weight
213.0637
Catelogue Number
MLS-LEV-EP-IMP-A/01
Synonym
(2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid|(2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic Acid;|(S)-2-amino-3-(2,4,5-trihydroxyphenyl)propanoic acid|2-Hydroxy Levodopa|2,4,5-Trihydroxy-L-phenylalanine;|2,4,5-Trihydroxyphenylalanine;|2,5-Dihydroxy-L-tyrosine;|3-(2,4,5-Trihydroxyphenyl)-L-alanine;|3-(3,4,6-Trihydroxyphenyl)-alanine|3-(3,4,6-Trihydroxyphenyl)-alanine;|3-(3,4,6-Trihydroxyphenyl)-L-alanine;|3-(3,4,6-Trihydroxyphenyl)alanine;|6-Hydroxy L-DOPA (Levadopa Related Compound A)|6-Hydroxy-L-DOPA;|Levodopa Related Compound A;|Levodopa USP Related Compound A|Levodopa USP Related Compound A ; (2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid; 3-(3,4,6-Trihydroxyphenyl)-alanine ; 2-Hydroxy Levodopa ;
Keywords
Amino Acids & Derivatives
Aromatics
Neurochemicals
Pharmaceuticals
Intermediates & Fine Chemicals
Levodopa EP Impurity A
6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. 6-Hydroxy L-DOPA (Levadopa Related Compound A)