For any information Email to: info@manasalifesciences.com

Category
Plerixafor
CAS Number
176252-20-3
Molecular Formula
C18H32N4O
Molecular Weight
320.47
Catelogue Number
MLS-PRX-IH-IMP-H/01
Synonym
(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)phenyl)methanol|(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)phenyl)methanol, hydrochloride (1:4)|4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)-Benzenemethanol; Plerixafor Impurity I;
Keywords
NA
Plerixafor Hydroxy Impurity
N-(4-Hydroxymethylbenzyl) Cyclam is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin’s lymphoma (NHL) and multiple myeloma (MM).