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Category
Palonosetron
CAS Number
135755-51-0 (HCl salt)
Molecular Formula
135755-51-0 (HCl salt)
Molecular Weight
342.43
Catelogue Number
MLS-PNS-IH-IMP-B/01
Synonym
(3aR,3S)-Palonosetron Formate Salt ; (3aR)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one formate salt ;|(5S)-3-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-3- azatricyclo[7.3.1.05,¹³]trideca-1(13),9,11-trien-2- one hydrochloride|(R,S)-Palonosetron HCl ;|(R)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride|(R)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one, hydrochloride (1:1)
Keywords
NA
Palonosetron Impurity B
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.