Tafenoquine

Tafenoquine was approved for medical use in Australia and in the United States in 2018. Tafenoquine was given an orphan drug designation and was granted breakthrough therapy status in 2013 in the United States.

Tafenoquine is an aminoquinoline that is used in combination with other antimalarials for the prevention of relapse of Plasmodium vivax malaria and by itself as prophylaxis against all species of malaria. Tafenoquine has been linked to low rates of transient and asymptomatic serum enzyme elevations during therapy but has not been associated with instances of clinically apparent acute liver injury.

Description

Tafenoquine was approved for medical use in Australia and in the United States in 2018. Tafenoquine was given an orphan drug designation and was granted breakthrough therapy status in 2013 in the United States.

Tafenoquine is an aminoquinoline that is used in combination with other antimalarials for the prevention of relapse of Plasmodium vivax malaria and by itself as prophylaxis against all species of malaria. Tafenoquine has been linked to low rates of transient and asymptomatic serum enzyme elevations during therapy but has not been associated with instances of clinically apparent acute liver injury.

 

Additional information

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