Bortezomib Impurity G

(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

Impurity in commercial preparations of Bortezomib

Bortezomib Impurity G

Bortezomib Impurity 48

White to Off-White Solid

Bortezomib Hydroxy Impurity (1S,2S)-Isomer

metabolites,impurities,pharmaceutical standards,intermediates,fine chemicals

SKU: 1834e5c572d1 Category: Tag:

Description

(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

Impurity in commercial preparations of Bortezomib

Bortezomib Impurity G

Bortezomib Impurity 48

Bortezomib Hydroxy Impurity (1S,2S)-Isomer

metabolites,impurities,pharmaceutical standards,intermediates,fine chemicals

White to Off-White Solid

Additional information

Synonym

, , , , , , , , , ,

CAS Number

Molecular Formula

Molecular Weight

Catalogue Number

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