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Category
Bortezomib
CAS Number
1132709-16-0
Molecular Formula
C19H25BN4O4
Molecular Weight
384.24
Catelogue Number
MLS-BOR-WS-ISO/01
Synonym
((S)-3-methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid|(1S,2R) Bortezomib|(1S,2R)-Bortezomib; [(1S)-3-Methyl-1-({(2R)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl} amino)butyl]boronic Acid|[(1S)-3-methyl-1-[(2R)-3-phenyl-2-(pyrazin-2-ylformamido)propanamido]butyl]boronc Acid|B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid|Bortezomib - In house impurity|Bortezomib (1S, 2R)-Isomer ; [(1S)-3-Methyl-1-({(2R)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl} amino)butyl]boronic acid ;|Bortezomib Impurity (1S,2R - Isomer)
Keywords
Chiral Reagents
Boron Derivatives
Inhibitors
Pharmaceuticals
Intermediates & Fine Chemicals
Bortezomib (1S, 2R)-Isomer
(1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway (1S,2R) Bortezomib Bortezomib Impurity (1S,2R - Isomer) Bortezomib - In house impurity chiral standards,boron derivatives,enzyme inhibitors,pharmaceutical standards,intermediates,fine chemicals